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Potency: In preclinical studies, Dihexa was found to be up to one million times more potent than BDNF in promoting synaptic connectivity highlighting its potential but also raising concerns about overstimulation
Adding a medication that intentionally slows digestion can sometimes create a double slow-down effect
These typically occur during dose escalation and often improve over time
Patients should be counselled about: Proper injection technique and storage requirements Recognition of adverse effects requiring medical attention The importance of continuing lifestyle modifications alongside medication Regular monitoring of blood glucose, HbA1c, and renal function When to seek urgent medical care (severe abdominal pain, persistent vomiting/diarrhoea with dehydration, sudden visual changes) Patients can report suspected side effects directly to the MHRA through the Yellow Card Scheme (yellowcard.mhra.gov.uk) as well as discussing them with their healthcare provider
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